In the Mid 1950's, Prof. Dyckerhoff develops the therapy with ribonucleic acids extracts. At this time, he is the director of the scientific department in the pharmaceutical factory Buer in Cologne, Germany. This work is the basis for the REGENERESEN products, which were applied to patients shortly after this development. The first publication on REGENERESEN treatments are published in 1957.
In 1963, Prof. Dyckerhoff founds the "Laboratorium Prof. Dr. H. Dyckerhoff GmbH & Co KG" together with his colleague Heinrich Klein and his wife Katharina. The production of the REGENERESEN products is know at his own company in Cologne Sülz. The distribution of REGENERESEN at this time lies at the Company Müller in Göppingen, Germany.
With steadily growing requirements for the production, the company does not have enough space at its current location in the densely populated quarter of Cologen Sülz. Thus, the company found a new site in a modern production surrounding in Cologne Longerich in 1991 where the company is situated until today.
In 1991, the product range was expanded by the ASmedic products. The first product was Harpagoforte, which contains the extract from the devils claw to treat e.g. inflammatory suffering at Joints. In 1997 the range gets further expanded by the B-Vitamin products.
Since 2012, Dyckerhoff-Extracts are produced as APIs for the final manufacture in pharmacies as individual extemporaneous mixture according to the therapy concept of Prof. Dyckerhoff. The REGENERESEN product range is no longer available after expiration of its registration. The ASmedic range gets complemented by Aqua ad Iniectabilia ex Colonia (water for injection) in glas ampoules. In 2019 the production and sale of Isotonic NaCl-solution ASmedic (saline solution) in 1 ml glass ampoules began.